From Michelle Ludlow [Michelle.Ludlow@dssmith.com]So far I have seen two different variants of the attachment doc4502094035.doc (VirusTotal  ) which according to these Malwr reports   download a malicious executable from the following locations:
Date Wed, 27 Jan 2016 17:27:22 +0800
Subject New Order
Please see attached for tomorrow.
Customer Services Co-Ordinator - Packaging Services
Dodwells Road, Hinckley LE10 3BX, United Kingdom
T +44 (0)1455 892939 F +44 (0)1455 892924
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This binary has a detection rate of 5/53. Those two Malwr reports and the VirusTotal report show the malware phoning home to:
22.214.171.124 (Loxley Wireless Co. Ltd., Thailand)
I strongly recommend that you block traffic to that IP. The payload is probably the Dridex banking trojan and this looks consistent with botnet 220 activity.